SidaGhanaV1, Main, Exploration, bibRecord, 000899

Low seroprevalence of cryptococcal antigenaemia in patients with advanced HIV infection enrolling in an antiretroviral programme in Ghana

Identifieur interne : 000899 ( Main/Exploration ); précédent : 000898; suivant : 000900

Low seroprevalence of cryptococcal antigenaemia in patients with advanced HIV infection enrolling in an antiretroviral programme in Ghana

Auteurs : Yaasir Mamoojee [Royaume-Uni] ; Shaid Shakoor [Royaume-Uni] ; Rebecca L. Gorton [Royaume-Uni] ; Stephen Sarfo [Ghana] ; Lambert T. Appiah [Ghana] ; Betty Norman [Ghana] ; Indran Balakrishnan [Royaume-Uni] ; Richard Phillips [Ghana] ; David Chadwick [Royaume-Uni]

Source :

TM & IH. Tropical medicine & international health [ 1360-2276 ] ; 2011.

RBID : Pascal:11-0033262

Descripteurs français

Pascal (Inist)
- SIDA, Sérologie, Antiviral, Prévalence, Cryptococcose, Antigène, Homme, Virus immunodéficience humaine, Sang, Stade avancé, Antirétroviral, Ghana, Epidémiologie, Médecine tropicale.
Wicri :
- geographic : Ghana.
- topic : Homme.

English descriptors

KwdEn :
- AIDS, Advanced stage, Antigen, Antiretroviral agent, Antiviral, Blood, Cryptococcosis, Epidemiology, Ghana, Human, Human immunodeficiency virus, Prevalence, Serology, Tropical medicine.

Abstract

OBJECTIVES To determine the prevalence of cryptococcal antigenaemia in a clinic population with advanced HIV infection, with a view to giving antifungal therapy to those testing positive. METHODS Serum samples from adults with CD4 count <100 cells/mm³ presenting to a large HIV clinic in Kumasi, Ghana, were tested retrospectively for cryptococcal antigenaemia using a latex agglutination assay, and clinical and demographic data extracted from case notes. RESULTS Of 92 samples tested, two were positive thus giving a prevalence of 2% (95% CI, 0-5.2%). CONCLUSIONS The prevalence of cryptococcal antigenaemia in patients with advanced HIV infection enrolling in an antiretroviral programme appears to be low in Kumasi, suggesting that the value of routine testing of outpatients diagnosed with advanced HIV infection may be limited in this population.

Affiliations:

Links toward previous steps (curation, corpus...)

to stream PascalFrancis, to step Corpus: 000032
to stream PascalFrancis, to step Curation: 000100
to stream PascalFrancis, to step Checkpoint: 000024
to stream Main, to step Merge: 000902
to stream Main, to step Curation: 000899

Le document en format XML

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<author><name sortKey="Balakrishnan, Indran" sort="Balakrishnan, Indran" uniqKey="Balakrishnan I" first="Indran" last="Balakrishnan">Indran Balakrishnan</name>
<affiliation wicri:level="3"><inist:fA14 i1="02"><s1>Department of Microbiology, The Royal Free Hospital</s1>
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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>AIDS</term>
<term>Advanced stage</term>
<term>Antigen</term>
<term>Antiretroviral agent</term>
<term>Antiviral</term>
<term>Blood</term>
<term>Cryptococcosis</term>
<term>Epidemiology</term>
<term>Ghana</term>
<term>Human</term>
<term>Human immunodeficiency virus</term>
<term>Prevalence</term>
<term>Serology</term>
<term>Tropical medicine</term>
</keywords>
<keywords scheme="Pascal" xml:lang="fr"><term>SIDA</term>
<term>Sérologie</term>
<term>Antiviral</term>
<term>Prévalence</term>
<term>Cryptococcose</term>
<term>Antigène</term>
<term>Homme</term>
<term>Virus immunodéficience humaine</term>
<term>Sang</term>
<term>Stade avancé</term>
<term>Antirétroviral</term>
<term>Ghana</term>
<term>Epidémiologie</term>
<term>Médecine tropicale</term>
</keywords>
<keywords scheme="Wicri" type="geographic" xml:lang="fr"><term>Ghana</term>
</keywords>
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<front><div type="abstract" xml:lang="en">OBJECTIVES To determine the prevalence of cryptococcal antigenaemia in a clinic population with advanced HIV infection, with a view to giving antifungal therapy to those testing positive. METHODS Serum samples from adults with CD4 count <100 cells/mm<sup>3</sup>
 presenting to a large HIV clinic in Kumasi, Ghana, were tested retrospectively for cryptococcal antigenaemia using a latex agglutination assay, and clinical and demographic data extracted from case notes. RESULTS Of 92 samples tested, two were positive thus giving a prevalence of 2% (95% CI, 0-5.2%). CONCLUSIONS The prevalence of cryptococcal antigenaemia in patients with advanced HIV infection enrolling in an antiretroviral programme appears to be low in Kumasi, suggesting that the value of routine testing of outpatients diagnosed with advanced HIV infection may be limited in this population.</div>
</front>
</TEI>
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<li>Royaume-Uni</li>
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<region><li>Angleterre</li>
<li>Grand Londres</li>
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<name sortKey="Balakrishnan, Indran" sort="Balakrishnan, Indran" uniqKey="Balakrishnan I" first="Indran" last="Balakrishnan">Indran Balakrishnan</name>
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<name sortKey="Gorton, Rebecca L" sort="Gorton, Rebecca L" uniqKey="Gorton R" first="Rebecca L." last="Gorton">Rebecca L. Gorton</name>
<name sortKey="Shakoor, Shaid" sort="Shakoor, Shaid" uniqKey="Shakoor S" first="Shaid" last="Shakoor">Shaid Shakoor</name>
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<country name="Ghana"><noRegion><name sortKey="Sarfo, Stephen" sort="Sarfo, Stephen" uniqKey="Sarfo S" first="Stephen" last="Sarfo">Stephen Sarfo</name>
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<name sortKey="Appiah, Lambert T" sort="Appiah, Lambert T" uniqKey="Appiah L" first="Lambert T." last="Appiah">Lambert T. Appiah</name>
<name sortKey="Norman, Betty" sort="Norman, Betty" uniqKey="Norman B" first="Betty" last="Norman">Betty Norman</name>
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	Le SIDA au Ghana (serveur d'exploration)
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Le SIDA au Ghana (serveur d'exploration)

Low seroprevalence of cryptococcal antigenaemia in patients with advanced HIV infection enrolling in an antiretroviral programme in Ghana

Low seroprevalence of cryptococcal antigenaemia in patients with advanced HIV infection enrolling in an antiretroviral programme in Ghana

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri